A number of mutations have been found at the ft locus relative to the sequenced strain, including a premature stop codon at position 805.
C4215428T
Q805term | ft-PA
Q805term
19 missense variants were identified in the ft locus in strain in addition to this nonsense mutation. Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.
ftQ805X clones generated in the larval eye disc lead to frequent ommatidial rotation phenotypes - planar cell polarity defects.
In eyes bearing ft8 clones, the clones are larger than control tissue, suggesting they have some competitive advantage; clonal regions in the eye disc show induction of apoptosis.
ftQ805X, numb15 has abnormal planar polarity | somatic clone phenotype, suppressible | partially by Scer\GAL4hs.2sev/numbUAS.cWa
ft8/ftQ805X, numb15 has abnormal cell polarity | adult stage phenotype
ftQ805X, numb15 has abnormal planar polarity | somatic clone | adult stage phenotype
ftQ805X, numb15 has abnormal planar polarity | somatic clone | larval stage phenotype
ftQ805X, numb15 has ommatidium | somatic clone phenotype, suppressible | partially by Scer\GAL4hs.2sev/numbUAS.cWa
ft8/ftQ805X, numb15 has posterior crossvein phenotype
ftQ805X, numb15 has ommatidium | somatic clone | larval stage phenotype
ftQ805X, numb15 has ommatidium | somatic clone | adult stage phenotype
Separable from: numb15.