hypomorphic allele - molecular evidence
A single-base deletion ( 3R:19850278 (Release 6)) in MICU3 that leads to a frameshift and early truncation. This mutation also substantially de-stabilizes the MICU3 transcript.
A 1bp deletion in the MICU3 coding region leads to a frameshift and early translation termination.
abnormal locomotor behavior | adult stage
short lived
viable
MICU327 mutant adults have a significant reduction in climbing ability at 2 days, and at 20 days, after eclosion, compared to controls.