FB2024_03 , released June 25, 2024
Allele: Dmel\ChTUAS.cHa
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General Information
Symbol
Dmel\ChTUAS.cHa
Species
D. melanogaster
Name
UAS construct a of Hamid
FlyBase ID
FBal0345607
Feature type
allele
Associated gene
Dmel\ChT
Associated Insertion(s)
Carried in Construct
P{UAS-ChT.H}
Also Known As
UAS-ChT
Key Links
Transgenic product class
cDNA
(Hamid et al., 2019)
wild_type
(Hamid et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Hamid et al., 2019)
wild_type
(Hamid et al., 2019)
Mutagen
in vitro construct
(Hamid et al., 2019)
Progenitor genotype
Carried in construct
P{UAS-ChT.H}
Cytology
Description

UASt regulates expression of a ChT cDNA.

(Hamid et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
ChT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      ChTUAS.cHa/Scer\GAL4GH146 rescues ChTKK109385

      (Hamid et al., 2021)

      ChTUAS.cHa/Scer\GAL4Gad1.3.098 rescues ChTKK109385

      (Hamid et al., 2021)
      Partially rescues

      ChTUAS.cHa/Scer\GAL4NP1131 partially rescues ChTKK109385

      (Hamid et al., 2021)

      ChTUAS.cHa/Scer\GAL4Mef2.247 partially rescues ChTKK109385

      (Hamid et al., 2021)

      ChTUAS.cHa/Scer\GAL4c305a partially rescues ChTKK109385

      (Hamid et al., 2021)

      ChTUAS.cHa/Scer\GAL4Orco.2.642.Hsim\VP22 partially rescues ChTKK109385

      (Hamid et al., 2021)

      Scer\GAL4GH298/ChTUAS.cHa partially rescues ChTKK109385

      (Hamid et al., 2021)

      ChTUAS.cHa/Scer\GAL4Tab2-201Y partially rescues ChTKK109385

      (Hamid et al., 2019)

      ChTUAS.cHa/Scer\GAL4NP1131 partially rescues ChTKK109385

      (Hamid et al., 2019)

      ChTUAS.cHa/Scer\GAL4NP6024 partially rescues ChTKK109385

      (Hamid et al., 2019)

      ChTUAS.cHa/Scer\GAL4ChAT.7.4 partially rescues ChTKK109385

      (Hamid et al., 2019)

      ChTUAS.cHa/Scer\GAL4nSyb.PS partially rescues ChTKK109385

      (Hamid et al., 2019)
      Fails to rescue

      ChTUAS.cHa/Scer\GAL4repo fails to rescue ChTKK109385

      (Hamid et al., 2019)
      Comments

      The eclosion defects induced when the expression of ChTKK109385 is under the control of Scer\GAL4Tab2-201Y, but not when under the control of Scer\GAL4repo, are suppressed by the co-expression of ChTUAS.cHa. The larval locomotion and neuromuscular junction defects induced by the Scer\GAL4Tab2-201Y-driven expression are also rescued by the co-expression of ChTUAS.cHa.

      The larval locomotion and neuromuscular defects, the increased mortality to pupation and the eclosion defects induced by the expression of ChTKK109385 under the control of either Scer\GAL4NP1131 or Scer\GAL4NP6024 are partially rescued by the co-expression of ChTUAS.cHa.

      The decreased larval locomotion induced by the expression of ChTKK109385 under the control of Scer\GAL4ChAT.7.4 is rescued by the co-expression of ChTUAS.cHa.

      The larval neuromuscular junction defects induced by the expression of ChTKK109385 under the control of Scer\GAL4nSyb.PS are rescued by the co-expression of ChTUAS.cHa.

      (Hamid et al., 2019)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ChTUAS.cHa
      Name Synonyms
      UAS construct a of Hamid
      Secondary FlyBase IDs
        References (2)