Removal of 15 bases, causing the deletion of 5 amino acids (deletion CGQVL), including the last cysteine in the RING finger domain, one amino acid prior to it, and the three amino acids that follow it. The reading frame is maintained after the deletion, thus this mutant likely expresses a form of the protein that is missing key residues to form the RING finger domain.
A deletion that removes amino acids 46-50 (CGQVL) of narya and leaves the reading frame intact.
Scer\GAL4VP16.nanos.UTR, naryaG4, nenyaRNAi.UAS has abnormal meiotic cell cycle | female phenotype
naryaG4 homozygous females that also express nenyadsRNA.UAS under the control of Scer\GAL4VP16.nos.UTR show frequent meiotic chromosome segregation errors, as assessed by X-chromosome non-disjunction. Although there are no obvious defects in meiotic recombination initiation in early pachytene cysts, as the frequent DSBs are still formed (i.e. γH2AV foci), this does not translate into crossovers along the X chromosome; however, this does not seem to be due to a global DSB repair defect, as there is no delay in the removal of γH2AV foci at mid-pachytene. The oocyte is correctly specified by early-mid pachytene but does not show any obvious defects in karyosome structure.
