FB2024_03 , released June 25, 2024
Allele: Dmel\variΔPDZ.UAS.Tag:HA
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General Information
Symbol
Dmel\variΔPDZ.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0335700
Feature type
allele
Associated gene
Dmel\vari
Associated Insertion(s)
Carried in Construct
P{UAS-vari.3xHA.ΔPDZ}
Key Links
Transgenic product class
inframe_deletion
(Jeong et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Jeong et al., 2017)
Mutagen
in vitro construct
(Jeong et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-vari.3xHA.ΔPDZ}
Cytology
Description

UASt regulatory sequences drive expression of an internally deleted form of vari that lacks the PDZ domain (lacks amino acid residues 158-259, coordinates according to GB:AAN11089.3). The protein is tagged with Tag:HA.

(Jeong et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
vari
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      variΔPDZ.UAS.Tag:HA/Scer\GAL4elav.PLu fails to rescue vari327

      (Jeong et al., 2017)
      Comments

      Expression of variΔPDZ.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav.PLu does not rescue the axon guidance defects observed in intersegmental nerve b motor axons of vari327 mutant embryos.

      (Jeong et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      variΔPDZ.Scer\UAS.T:Ivir\HA1
      variΔPDZ.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)