The GMR10E05 enhancer fragment followed by the Drosophila synthetic core promoter (DSCP) is fused upstream of the GAL4(DBD)::Zip- hemidriver (component of the 'Split GAL4' system, contains the GAL4 DNA-binding domain).
Comment: when combined with P{R28F07-p65.AD} (combination referred to as 'MB425B')
Comment: when combined with P{R28F07-p65.AD} (combination referred to as 'MB425B')
Blocking synaptic transmission (using shits1.IVS.p10.20xScer\UAS at 33[o]C) from neurons targeted by the split-GAL4 combination of Scer\GAL4DBD.R10E05 and Hsap\RELAAD.R28F07 significantly impairs visual (aversive color discrimination conditioning) memory performance, compared to controls; there is no significant effect on memory after brightness discrimination conditioning.