FB2024_03 , released June 25, 2024
Allele: Scer\GAL4mbl-MI00139-TG4.0
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General Information
Symbol
Scer\GAL4mbl-MI00139-TG4.0
Species
S. cerevisiae
Name
FlyBase ID
FBal0328020
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

The RMCE cassette of the Mi{MIC}mblMI00139 insertion has been replaced with a Trojan-GAL4 cassette. The insertion is in a coding intron of mbl and is predicted to gene trap the gene. (Note that if this gene has multiple transcripts, only those where the insertion is in a coding intron are predicted to be trapped).

Allele components
Component
Use(s)
Mutations Mapped to the Genome
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
distribution deduced from reporter or direct label
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

The translational mbl reporter is expressed in third instar larval photoreceptors. In the brain, expression is observed mainly in post-mitotic neurons with some expression in glial cells. It is also detected in muscles. An intersectional strategy was used to label single cells. mbl reporter is observed in L1, L4, R7 and R8 neurons. mbl is expressed in a cell-specific manner that correlates with the expression of Dscam2 exon 10B but not 10A. It is not detected in mushroom body neurons that express Dscam2 exon 10A in adults.

 
Marker for
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Scer\GAL4mbl-MI00139-TG4.0
Name Synonyms
Secondary FlyBase IDs
    References (5)