The expression of Hsap\MAPTUAS.0N3R.cFa under the control of Scer\GAL4sim.PS stimulates mitosis in the ventral midline of stage 13 embryos.
Expression of Hsap\MAPTScer\UAS.0N3R.cFa under the control of Scer\GAL4nSyb.PS leads to significantly reduced adult lifespan.
Hsap\MAPTUAS.0N3R.cFa, Scer\GAL4elav-C155 has short lived phenotype, enhanceable by MicalUAS.EGFP, Scer\GAL4elav-C155
Hsap\MAPTUAS.0N3R.cFa, Scer\GAL4elav-C155 has short lived phenotype, suppressible by MicalNIG.18668R, Scer\GAL4elav-C155
Hsap\MAPTUAS.0N3R.cFa, Scer\GAL4nSyb.PS is an enhancer of short lived phenotype of Hsap\TTBK1UAS.Tag:MYC,Tag:HA, Scer\GAL4nSyb.PS
The co-expression of Hsap\MAPTUAS.0N3R.cFa and MicalUAS.EGFP under the control of Scer\GAL4elav-C155 leads to decreased memory in olfactory aversive conditioning assays.
The reduced adult lifespan caused by expression of Hsap\TTBK1Scer\UAS.T:Hsap\MYC,T:Ivir\HA1 is also exacerbated by co-expression of Hsap\MAPTScer\UAS.0N3R.cFa.