FB2024_03 , released June 25, 2024
Allele: Dmel\FIG4UAS.Tag:MYC
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General Information
Symbol
Dmel\FIG4UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0322832
Feature type
allele
Associated gene
Dmel\FIG4
Associated Insertion(s)
Carried in Construct
P{UAS-Myc-FIG4.WT}
Key Links
Transgenic product class
wild_type
(Bharadwaj et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bharadwaj et al., 2016)
Mutagen
in vitro construct
(Bharadwaj et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-Myc-FIG4.WT}
Cytology
Description

UAS regulatory sequences drive expression of FIG4 tagged at the N-terminal end with Tag:MYC.

(Bharadwaj et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
FIG4
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      FIG4UAS.Tag:MYC/Scer\GAL4Mef2.PU rescues FIG4Δ1

      (Bharadwaj et al., 2016)
      Comments

      The lysosome expansion phenotype observed in somatic muscles of FIG4Δ1 homozygous third instar larvae is fully or partially rescued by expression of any of the following: FIG4Scer\UAS.T:Hsap\MYC, FIG4I41T.Scer\UAS.T:Hsap\MYC, FIG4L17P.Scer\UAS.T:Hsap\MYC, FIG4D53Y.Scer\UAS.T:Hsap\MYC or FIG4C450S.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4Mef2.PU in the mutant background.

      (Bharadwaj et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      FIG4Scer\UAS.T:Hsap\MYC
      FIG4UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)