FB2024_03 , released June 25, 2024
Allele: Dmel\Eip75BΔC
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General Information
Symbol
Dmel\Eip75BΔC
Species
D. melanogaster
Name
FlyBase ID
FBal0320747
Feature type
allele
Associated gene
Dmel\Eip75B
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
FLPase
(Rabinovich et al., 2016)
Progenitor genotype
PBac{RB}Eip75Be01229
(Rabinovich et al., 2016)
PBac{RB}e03151
(Rabinovich et al., 2016)
Cytology
Description

Deletion that specifically affects the Eip75B C isoform.

(Rabinovich et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eip75BΔC/Eip75BΔC mutant mushroom body neuron clones fail to fully innervate the adult gamma lobe during regrowth at metamorphosis, and also contain fewer axons, but there is no defect in initial extension of these neurons, as compared to wild type.

      (Rabinovich et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Eip75BΔC is rescued by Eip75BUAS.C.Tag:FLAG/Scer\GAL4Tab2-201Y

      (Rabinovich et al., 2016)
      Comments

      Expression of Eip75BScer\UAS.C.T:Zzzz\FLAG under the control of Scer\GAL4Tab2-201Y significantly rescues the gamma lobe regrowth defects of Eip75BΔC/Eip75BΔC mushroom body neuron clones.

      (Rabinovich et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      E75ΔC
      (Rabinovich et al., 2016)
      Eip75BΔC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)