UASt regulatory sequences drive expression of the Hsap\DNM1L reference (wild-type) sequence.
Expression of Hsap\DNM1LScer\UAS.cCa under the control of either Scer\GAL4Act5C.PI or Scer\GAL4Mef2.PU does not cause lethality.
Expression of Hsap\DNM1LScer\UAS.cCa under the control of Scer\GAL4Act5C.PI does not affect peroxisome morphology or their number per cell in the salivary glands of third instar larvae.
Scer\GAL4da.PU/Hsap\DNM1LUAS.cCa is a suppressor of lethal phenotype of Drp12/Drp11
The lethality of Drp11/Drp12 transheterozygotes is rescued by expression of Hsap\DNM1LScer\UAS.cCa under the control of Scer\GAL4da.PU in the mutant background.
Expression of Hsap\DNM1LScer\UAS.cCa under the control of either Scer\GAL4Act5C.PI or Scer\GAL4Mef2.PU does not cause lethality when expressed in sensitised Drp11/+ background.
Expression of Hsap\DNM1LScer\UAS.cCa under the control of Scer\GAL4Mef2.PU in sensitised Drp11/+ background does not cause any defects in the morphology or number of mitochondria in third instar larval muscles. Expression under the control of Scer\GAL4Toll-6-D42 also does not cause mitochondria trafficking defects in the ventral nerve cord, axons and synaptic boutons (though number of mitochondria per bouton is slightly lower compared to controls) in third instar larvae.