UAS regulatory sequences drive expression of a short inverted repeat.
eye, with Scer\GAL4ey.PU
The expression of RNF220HMJ23135 under the control of Scer\GAL4GMR.PU leads to strong retina degeneration.
The expression of RNF220HMJ23135 under the control of Scer\GAL4ey.PU at high levels (flies reared at 25[o]C) leads to lethality, whereas at lower levels (flies reared at 18[o]C) leads to severe alterations in eye development, linked to a significant reduction in the eye surface.