FlyBase Allele Report: Dmel\Sema2a[unspecified]

General Information

Symbol

Dmel\Sema2a^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0301594

Feature type

allele

Associated gene

Dmel\Sema2a

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

oocyte | somatic clone

(Kucherenko et al., 2008)

Detailed Description

Statement

Reference

Sema-2a^unspecified mutant germline clones show oocyte mislocalisation. Oogenesis arrests at stage 4-6.

(Kucherenko et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Sema-2a[+]/Sema2a^unspecified is an enhancer of visible phenotype of Dg^RNAi.UAS, Scer\GAL4^Tub.PU

(Kucherenko et al., 2008)

Suppressor of

Statement

Reference

Sema-2a[+]/Sema2a^unspecified is a suppressor of visible phenotype of Dys^RNAi.NH2.UAS, Scer\GAL4^Act.PU

(Kucherenko et al., 2008)

Sema-2a[+]/Sema2a^unspecified is a suppressor of visible phenotype of Dys^RNAi.C.UAS, Scer\GAL4^Tub.PU

(Kucherenko et al., 2008)

Other

Statement

Reference

Dys^E6, Sema-2a[+]/Sema2a^unspecified has visible phenotype

(Kucherenko et al., 2008)

Phenotype Manifest In

Enhancer of

Statement

Reference

Sema-2a[+]/Sema2a^unspecified is an enhancer of posterior crossvein phenotype of Dg^RNAi.UAS, Scer\GAL4^Tub.PU

(Kucherenko et al., 2008)

Suppressor of

Statement

Reference

Sema-2a[+]/Sema2a^unspecified is a suppressor of posterior crossvein phenotype of Dys^RNAi.NH2.UAS, Scer\GAL4^Act.PU

(Kucherenko et al., 2008)

Sema-2a[+]/Sema2a^unspecified is a suppressor of posterior crossvein phenotype of Dys^RNAi.C.UAS, Scer\GAL4^Tub.PU

(Kucherenko et al., 2008)

Other

Statement

Reference

Dys^E6, Sema-2a[+]/Sema2a^unspecified has posterior crossvein phenotype

(Kucherenko et al., 2008)

Dys^RNAi.C.UAS, Sema-2a[+]/Sema2a^unspecified has wing vein | ectopic phenotype

(Kucherenko et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

One copy of Sema-2a^unspecified weakly suppresses the detached posterior crossvein phenotype seen when Dys^{dsRNA.NH2.Scer\UAS} is expressed under the control of Scer\GAL4^Act.PU.

One copy of Sema-2a^unspecified weakly suppresses the detached posterior crossvein phenotype seen when Dys^{dsRNA.C.Scer\UAS} is expressed under the control of Scer\GAL4^tub.PU but produces extra wing vein material.

One copy of Sema-2a^unspecified in a Dys^E6/+ background results in posterior crossvein defects.

One copy of Sema-2a^unspecified enhances the posterior crossvein phenotype seen when Dg^{dsRNA.Scer\UAS} is expressed under the control of Scer\GAL4^tub.PU.

(Kucherenko et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Sema-2a^unspecified

Sema2a^unspecified

sema-2a^k13416

(Kucherenko et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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