FB2024_03 , released June 25, 2024
Allele: Scer\GAL4Wnt5-Gal4
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General Information
Symbol
Scer\GAL4Wnt5-Gal4
Species
S. cerevisiae
Name
FlyBase ID
FBal0301550
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
TI{GAL4}Wnt5Gal4
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ends-out gene targeting
(Wu et al., 2014)
Progenitor genotype
Associated Insertion(s)
TI{GAL4}Wnt5Gal4
Cytology
Description

Precise replacement of the Wnt5 gene with sequence encoding a GAL4 driver.

(Wu et al., 2014)
Allele components
Component
Use(s)
Inserted element
TI{GAL4}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      prepupal stage P1 -- P3
      antennal lobe

      Comment: 0h-6h APF

      (Wu et al., 2014)
      prepupal stage P1 -- pupal stage P6
      neuron projection bundle | restricted

      Comment: 0h-24h APF

      (Wu et al., 2014)
      pupal stage P5
      neuron | subset of deutocerebrum

      Comment: 16h APF

      (Wu et al., 2014)
      pupal stage P5 -- P6
      antennal nerve

      Comment: 16h-24h APF

      (Wu et al., 2014)
      Additional Information
      Statement
      Reference

      ScerGAL4Wnt5-Gal4 drives expression in the degenerating larval antennal lobes during the first hours of pupal development. Labeling is also detected in a cluster of 20-30 neurons located in the deuterocerebrum, anterior and lateral to the antennal lobe. Its axons fasciculate in a developing neuron projection bundle terminating at the anterior dorsolateral edge of the developing adult antennal lobe. At 16h APF ScerGAL4Wnt5-Gal4 also drives expression in the developing adult antennal nerve which is strongly labeled at 24h APF.

      (Wu et al., 2014)
       
      Marker for
      Reflects expression of
      Wnt5
      (Wu et al., 2014)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4Wnt5-Gal4
      Name Synonyms
      Secondary FlyBase IDs
        References (1)