Amino acid replacement: T183A.
Amino acid replacement: Y185A.
Overexpression of p38bkd.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4P0.5.Pdf under free-running conditions leads to a further increase in the number of arrhythmic animals compared with wild-type overexpression. Overexpression of p38bkd.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4cry.PZ (which is more widely expressed than Scer\GAL4P0.5.Pdf), results in a further increase in period length.
Scer\GAL4cry.PZ, p38bDD.UAS has abnormal circadian rhythm phenotype, non-enhanceable by per01/per[+]
Scer\GAL4cry.PZ, p38bDD.UAS has abnormal circadian rhythm phenotype, non-suppressible by per01/per[+]
A per01 heterozygous background does not greatly affect the tau or arrhythmicity seen upon expression of p38bDD.Scer\UAS.