Expression of fraScer\UAS.cOa.T:Hsap\MYC in an ipsilaterally projecting subset of neurons, under the control of Scer\GAL4ap-md544, results in axons from these neurons projecting aberrantly across the midline.
Scer\GAL4ap-md544, fraUAS.cOa.Tag:MYC has abnormal neuroanatomy phenotype, suppressible by Df(1)NetABΔ
Scer\GAL4ap-md544, fraUAS.cOa.Tag:MYC has larval EW neuron phenotype, suppressible by Df(1)NetABΔ
A Df(1)NetABΔ background suppresses the aberrant midline crossing seen in ipsilaterally-projecting neurons expressing fraScer\UAS.cOa.T:Hsap\MYC under the control of Scer\GAL4ap-md544.
Expression of fraScer\UAS.cOa.T:Hsap\MYC in all neurons, through expression under the control of Scer\GAL4elav.PLu, rescues EW midline crossing defects in fra3/fra4 mutants.
Expression of fraScer\UAS.cOa.T:Hsap\MYC in all neurons, through expression under the control of Scer\GAL4elav.PLu, fully rescues fra3 commissural axon defects.