UAS regulatory sequences drive expression of mutated drosha coding sequences containing a 441bp deletion, removing amino acids 561-707. This construct is tagged at the C-terminal with Tag:FLAG.
abnormal neuroanatomy, with Scer\GAL4ey-OK107
alpha'/beta' Kenyon cell, with Scer\GAL4ey-OK107
Expression of droshaΔ.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4ey-OK107 in an otherwise wild-type background results in overgrowth of α/β neurons.
Scer\GAL4ey-OK107/droshaΔ.UAS.Tag:FLAG fails to rescue drosha21K11