FB2024_03 , released June 25, 2024
Allele: Dmel\rigΔN.UAS
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General Information
Symbol
Dmel\rigΔN.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0294751
Feature type
allele
Associated gene
Dmel\rig
Associated Insertion(s)
Carried in Construct
P{UAS-rig.ΔN}
Key Links
Transgenic product class
inframe_deletion
(Borg and Cauchi, 2013)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Borg and Cauchi, 2013)
Mutagen
in vitro construct
(Borg and Cauchi, 2013)
Progenitor genotype
Carried in construct
P{UAS-rig.ΔN}
Cytology
Description

UAS regulatory sequences drive expression of a mutant form of rig lacking the N-terminal domain.

(Borg and Cauchi, 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
rig
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of rigΔN.Scer\UAS driven by Scer\GAL4Mef2.PR does not significantly affect flight or lifespan.

      (Borg et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Gem3ΔN.Scer\UAS and rigΔN.Scer\UAS driven by Scer\GAL4Mef2.PR results in flightless flies with shortened lifespans (compared to either single expression, which is similar to controls).

      (Borg et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL41032.hx/rigΔN.UAS fails to rescue rigNIG.11171R

      (Borg and Cauchi, 2013)
      Comments

      Expression of rigΔN.Scer\UAS fails to rescue the lethality seen when rigNIG.11171R is expressed under the control of Scer\GAL41032.hx.

      (Borg and Cauchi, 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      rigΔN.Scer\UAS
      rigΔN.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)