FB2024_03 , released June 25, 2024
Allele: Dmel\ctUAS.cUa
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General Information
Symbol
Dmel\ctUAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0291677
Feature type
allele
Associated gene
Dmel\ct
Associated Insertion(s)
Carried in Construct
P{UAS-ct.U}
Also Known As
UAS-cut, UAS-Ct
Key Links
Transgenic product class
wild_type
(Anderson et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Anderson et al., 2012)
Mutagen
in vitro construct
(Anderson et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-ct.U}
Cytology
Description

UAS regulatory sequences drive expression of ct.

(Anderson et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
ct
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In distal tip/mid-air sac primordium clones expressing ctUAS.cUa under the control of Scer\GAL4btl.B123, the mutant cells produce significantly fewer long and oriented cytonemes compared to the control clones at an equivalent position; however, the orientation and number of cytonemes from the ASP stalk cells, remained unaffected compared to control clones.

      (Du et al., 2018)

      Expressing ctUAS.cUa under the control of Scer\GAL4221 results in a significantly increased number of branch points in the dendrites of class I dendritic arborizing neurons in third instar larvae compared to wild-type controls.

      (Kwon et al., 2018)

      Overexpression of ctScer\UAS.cUa driven by Scer\GAL4109(2)80 or Scer\GAL42-21 leads to a significant increase in dendrite branch points and length in class I da sensory neurons compared to wild type, along with formation of dendritic spike morphology.

      (Bagley et al., 2014)

      Low-level ectopic expression of ctUAS.cUa under the control of Scer\GAL4btl.PS (in combination with a Gal80[ts] transgene to generate different levels of expression at different temperatures) inhibits tracheal differentiation and stimulates proliferation in cells located at spiracular branch (SB) growth zone 1 at 25[o]C.

      High-level ectopic expression of ctUAS.cUa under the control of Scer\GAL4btl.PS (in combination with a Gal80[ts] transgene to generate different levels of expression at different temperatures) leads to an almost complete elimination of cells in SB growth zones 1 and 2, an impaired growth of SB and a reduction in the number of pH3+ cells in SB growth zone 2 at 29[o]C.

      (Pitsouli and Perrimon, 2013)

      Expression of ctScer\UAS.cUa under the control of Scer\GAL4ey.PU converts the eye into a duplicate antenna.

      (Anderson et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      NOT suppressed by
      Suppressor of
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of ctScer\UAS.cUa driven by Scer\GAL4109(2)80 does not suppress the reduction of dendritic spikes in class III da sensory neuron fs(1)h1112/fs(1)h1112 larval clones.

      Loss of fs(1)h1112/fs(1)h1112 in class I da neuron clones suppresses the increase in dendrite branch points and length and formation of dendritic spike morphology seen in larvae with ctScer\UAS.cUa overexpression driven by Scer\GAL4109(2)80.

      Co-expression of fs(1)hScer\UAS.T:Avic\GFP-EGFP partially suppresses the increase in dendrite branch points and length in class I da neurons seen in larvae with ctScer\UAS.cUa overexpression driven by Scer\GAL42-21.

      (Bagley et al., 2014)

      In spiracular branch (SB) growth zones 2 and 4, expression of ctUAS.cUa under the control of Scer\GAL4ct-PG142 partially suppresses the decreased number of SB cell phenotype caused by expression of panΔN.UAS under the control of Scer\GAL4ct-PG142 (in combination with a Gal80[ts] transgene to overexpress ctUAS.cUa and panΔN.UAS in the SB temporally).

      (Pitsouli and Perrimon, 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ctScer\UAS.cUa
      ctUAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Unknown
      Secondary FlyBase IDs
        References (12)