FB2024_03 , released June 25, 2024
Allele: Dmel\EpacUAS.cEa
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General Information
Symbol
Dmel\EpacUAS.cEa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Efetova
FlyBase ID
FBal0287551
Feature type
allele
Associated gene
Dmel\Epac
Associated Insertion(s)
Carried in Construct
P{UAS-Epac.E}
Key Links
Transgenic product class
cDNA
(Efetova et al., 2013)
wild_type
(Efetova et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Efetova et al., 2013)
wild_type
(Efetova et al., 2013)
Mutagen
in vitro construct
(Efetova et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-Epac.E}
Cytology
Description

UASt regulatory sequences drive expression of the full-length Epac cDNA GH01501, which encodes the RD isoform.

(Efetova et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Epac
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      EpacUAS.cEa, Scer\GAL4c42 is an enhancer of Malpighian tubule | conditional phenotype of Besp\bPACUAS.cSa, Scer\GAL4c42

      (Efetova et al., 2013)

      EpacUAS.cEa, Scer\GAL4tsh-c724 is an enhancer of Malpighian tubule | conditional phenotype of Besp\bPACUAS.cSa, Scer\GAL4tsh-c724

      (Efetova et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of EpacScer\UAS.cEa elevates light activated stimulation of fluid secretion from the Malpighian tubules caused by expression of Zzzz\bPACScer\UAS.cSa under the control of Scer\GAL4c42, but has no effect on basal secretion rates.

      Co-expression of EpacScer\UAS.cEa elevates both basal and stimulated fluid secretion from the Malpighian tubules caused by expression of Zzzz\bPACScer\UAS.cSa under the control of Scer\GAL4tsh-c724.

      (Efetova et al., 2013)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      EpacScer\UAS.cEa
      EpacUAS.cEa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Efetova
      Secondary FlyBase IDs
        References (2)