Ubi-p63E promoter sequences drive expression of mys coding sequences carrying a predicted activating mutation in the transmembrane domain (carries the amino acid replacement L796R, which mimics talin-induced conformational changes by shortening the length of transmembrane domain that is buried in the plasma membrane).
mysL796R.EYFP.Ubi-p63E partially rescues mys11
Expression of mysL796N.T:Avic\GFP-EYFP.Ubi-p63E partially rescues the germband retraction phenotype and almost completely rescues the dorsal closure phenotype found in mys11 embryos.
The mysL796N.T:Avic\GFP-EYFP.Ubi-p63E transgene rescues the muscle detachment phenotype seen in mys11 embryos.