Amino acid residue Cys218 of Hsap\PTEN has been mutated to Ser.
Expression of Pten::Hsap\PTENDH218.Scer\UAS under the control of Scer\GAL4GMR.PF results in a small eye phenotype, with the ommatidia being reduced in size relative to wild type.
Pten::Hsap\PTENDH218.UAS, Scer\GAL4GMR.PF has visible phenotype, non-suppressible by Hsap\TXNUAS.cSa, Scer\GAL4GMR.PF
Pten::Hsap\PTENDH218.UAS, Scer\GAL4GMR.PF has eye phenotype, non-suppressible by Hsap\TXNUAS.cSa, Scer\GAL4GMR.PF
Pten::Hsap\PTENDH218.UAS, Scer\GAL4GMR.PF has ommatidium phenotype, non-suppressible by Hsap\TXNUAS.cSa, Scer\GAL4GMR.PF
Co-expression of Hsap\TXNScer\UAS.cSa does not rescue the small eye and ommatidium phenotype caused by expression of Pten::Hsap\PTENDH218.Scer\UAS under the control of Scer\GAL4GMR.PF.