FB2024_03 , released June 25, 2024
Allele: Dmel\DgPPSG.UASp
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General Information
Symbol
Dmel\DgPPSG.UASp
Species
D. melanogaster
Name
FlyBase ID
FBal0280269
Feature type
allele
Associated gene
Dmel\Dg
Associated Insertion(s)
Carried in Construct
P{UASp-Dg.PPSG}
Key Links
Transgenic product class
missense_variant
(Yatsenko et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Yatsenko et al., 2009)
Mutagen
in vitro construct
(Yatsenko et al., 2009)
Progenitor genotype
Carried in construct
P{UASp-Dg.PPSG}
Cytology
Description

UASp regulatory sequences drive expression of a mutated form of Dg in which the N-terminal WW binding motif, WWbsII, is changed from PPSY to PPSG.

(Yatsenko et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Dg
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of DgPPSG.Scer\UAS.P\T using Scer\GAL4mat.αTub67C.T:Hsim\VP16 generates oocyte polarity defects.

      (Yatsenko et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4VP16.nanos.UTR/DgPPSG.UASp partially rescues Dg323

      (Yatsenko et al., 2009)
      Comments

      The oocyte polarity and developmental arrest phenotypes shown by Dg323 germline clones are partially rescued by Scer\GAL4nos.UTR.T:Hsim\VP16-mediated expression of DgPPSG.Scer\UAS.P\T.

      (Yatsenko et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DgPPSG.Scer\UAS.P\T
      DgPPSG.UASp
      Name Synonyms
      Secondary FlyBase IDs
        References (1)