Amino acid replacement: R373C.
UASt regulatory sequences drive expression of mutated Hsap\PROM1 coding sequences.
Expression of Hsap\PROM1R373C.Scer\UAS in the developing eye, under the control of Scer\GAL4GMR.PF results in the disruption of the organization of the F-actin within the developing rhabdomeres by 84 hours after pupal formation.
Hsap\PROM1R373C.UAS/Scer\GAL4GMR.PF is a non-suppressor of rhabdomere phenotype of prom1
Hsap\PROM1R373C.UAS/Scer\GAL4GMR.PF is a non-suppressor of eye phenotype of prom1
Expression of Hsap\PROM1R373C.Scer\UAS in the developing eye, under the control of Scer\GAL4GMR.PF, is not sufficient to suppress the rhabdomere phenotype in prom1 mutants.