FB2024_03 , released June 25, 2024
Allele: Rat\NeuYC.UAS
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General Information
Symbol
Rat\NeuYC.UAS
Species
R. unknown
Name
FlyBase ID
FBal0269182
Feature type
allele
Associated gene
Rat\Neu
Associated Insertion(s)
Carried in Construct
P{UAS-Neu.YC}
Transgenic product class
missense_variant
(Settle et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Settle et al., 2003)
Mutagen
in vitro construct
(Settle et al., 2003)
Progenitor genotype
Rat\NeuNYPD.UAS
(Settle et al., 2003)
Carried in construct
P{UAS-Neu.YC}
Cytology
Description

Amino acid residue 1201 has been restored to a Tyr residue.

(Settle et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Rat\Neu
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Rat\NeuYC.Scer\UAS under the control of Scer\GAL4sim.P3.7 results in a slightly increased number of midline glia cells compared to wild type at stage 16 of embryogenesis.

      The 1.3% of animals expressing Rat\NeuYC.Scer\UAS under the control of Scer\GAL4GMR.PU which survive to eclosion have a severely reduced eye with no ommatidial structure.

      Flies expressing Rat\NeuYC.Scer\UAS under the control of Scer\GAL4bbg-C96 have notches on the the wing margin.

      (Settle et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Rat\NeuYC.Scer\UAS
      Rat\NeuYC.UAS
      neuYC
      (Settle et al., 2003)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)