Mutation of three consensus Glu residues in Ubiquitin interaction motif (UIM) 1 to Ala.
lqfUIM1.EA.GFP rescues lqfFDD9
lqfUIM1.EA.GFP partially rescues lqfL71/lqfARI
lqfUIM1.EA.T:Avic\GFP rescues the lethality of lqfARI/lqfL71 animals and the resulting adults are almost wild type (68 +/- 12% of facets in the eye are normal).