FB2024_03 , released June 25, 2024
Allele: Dmel\ckAN9
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General Information
Symbol
Dmel\ckAN9
Species
D. melanogaster
Name
FlyBase ID
FBal0267126
Feature type
allele
Associated gene
Dmel\ck
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Bejsovec and Chao, 2012)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q456L.

(Bejsovec and Chao, 2012)

Nucleotide substitution: A?T.

(Bejsovec and Chao, 2012)

Amino acid replacement: S1577G.

(Bejsovec and Chao, 2012)

Nucleotide substitution: A?G.

(Bejsovec and Chao, 2012)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:15,050,926..15,050,926 [-]
Nucleotide change:

A15050926T

Reported nucleotide change:

A?T

Amino acid change:

Q456L | ck-PA; Q456L | ck-PB; Q456L | ck-PC; Q456L | ck-PD

Reported amino acid change:

Q456L

(Bejsovec and Chao, 2012)
point_mutation
2L:15,047,447..15,047,447 [-]
Nucleotide change:

A15047447G

Reported nucleotide change:

A?G

Amino acid change:

S1577G | ck-PA; S1577G | ck-PB; S1577G | ck-PC; S1577G | ck-PD

Reported amino acid change:

S1577G

(Bejsovec and Chao, 2012)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos do not have any obvious denticle morphology defects in the denticle belts.

      (Bejsovec and Chao, 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Other
      Statement
      Reference

      ckAN9, wgl-17 has denticle phenotype

      (Bejsovec and Chao, 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      ckAN9 modifies the wgl-17 denticle phenotype, such that the double mutants have denticles with a rounded appearance and no distinctive hook.

      (Bejsovec and Chao, 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ckAN9
      (Bejsovec and Chao, 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)