FB2024_03 , released June 25, 2024
Allele: Dmel\Sas-4ΔPN2-3
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General Information
Symbol
Dmel\Sas-4ΔPN2-3
Species
D. melanogaster
Name
FlyBase ID
FBal0264846
Feature type
allele
Associated gene
Dmel\Sas-4
Associated Insertion(s)
Carried in Construct
P{Sas-4.ΔPN2-3}
Key Links
Transgenic product class
inframe_deletion
(Gopalakrishnan et al., 2011)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Gopalakrishnan et al., 2011)
Mutagen
in vitro construct
(Gopalakrishnan et al., 2011)
Progenitor genotype
Carried in construct
P{Sas-4.ΔPN2-3}
Cytology
Description

A mutant lacking residues 103-121 (the 19 residues conserved in the PN2-3 domain) of the wild-type Sas-4 polypeptide is expressed under the control of a Sas-4 promoter.

(Gopalakrishnan et al., 2011)
Allele components
Component
Use(s)
Regulatory region(s)
Sas-4
Encoded product / tool
Sas-4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Sas-4ΔPN2-3 partially rescues Sas-4s2214

      (Gopalakrishnan et al., 2011)
      Comments

      Sas-4ΔPN2-3 partially rescues the Sas-4s2214 uncoordinated phenotype. Flies expressing Sas-4ΔPN2-3 in a Sas-4s2214 mutant background are unable to stand.

      Unlike Sas-4s2214 mutants, flies expressing Sas-4ΔPN2-3 have normal number of centrosomes.

      (Gopalakrishnan et al., 2011)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Sas-4ΔPN2-3
      Name Synonyms
      Secondary FlyBase IDs
        References (1)