FlyBase Allele Report: Dmel\ct[HMS00924]

Expressing ct^HMS00924 under the control of Scer\GAL4^ppk.PU results in a significantly reduced number of branch points in the dendrites of class IV dendritic arborizing neurons in third instar larvae compared to wild-type controls.

(Kwon et al., 2018)

Adult escapers expressing ct^HMS00924 under the control of Scer\GAL4^esg-NP5130 show ureters that are short and lack the lower region, have increased numbers of progenitor cells and have decreased numbers of principal cells, which disperse throughout the ureter and lower tubule, as compared to controls; renal tubule clones expressing ct^HMS00924 under the control of Scer\GAL4^esg-NP5130 display ectopic enteroendocrine-like cells (i.e. Pros-, Rab3-, Brp- and Ast A-positive, diploid cells) along the tubules, as compared to controls.

(Xu et al., 2018)

Expression of ct^HMS00924 under the control of Scer\GAL4^ppk.1.9 results in strong and penetrant phenotypes in C-IV neurons but no phenotypes in C-I neurons. DdaC, v'ada and vdaB neurons all have reduced total dendritic length compared to controls. The total number of dendritic branches is also reduced in ddaC and v'ada and vdaB neurons.

(Iyer et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^NP5130, ct^HMS00924 has increased cell number | somatic clone phenotype, enhanceable by N^VDRC.cUa, Scer\GAL4^NP5130

(Xu et al., 2018)

NOT suppressed by

Statement

Reference

Scer\GAL4^Mef2.PR, ct^HMS00924 has flightless phenotype, non-suppressible by salm^KK106735/Scer\GAL4^Mef2.PR

(Katti et al., 2022)

NOT Enhancer of

Statement

Reference

ct^HMS00924, Scer\GAL4^NP5130 is a non-enhancer of decreased cell number | somatic clone phenotype of N^VDRC.cUa, Scer\GAL4^NP5130

(Xu et al., 2018)

Suppressor of

Statement

Reference

ct^HMS00924, Scer\GAL4^NP5130 is a suppressor of decreased cell number | somatic clone phenotype of N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^NP5130

(Xu et al., 2018)

NOT Suppressor of

Statement

Reference

ct^HMS00924/Scer\GAL4^Mef2.PR is a non-suppressor of flightless phenotype of Scer\GAL4^Mef2.PR, salm^KK106735

(Katti et al., 2022)

ct^HMS00924, Scer\GAL4^NP5130 is a non-suppressor of increased cell number | somatic clone phenotype of N^VDRC.cUa, Scer\GAL4^NP5130

(Xu et al., 2018)

Other

Statement

Reference

N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^NP5130, ct^HMS00924 has increased cell number phenotype

(Xu et al., 2018)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^NP5130, ct^HMS00924 has adult ureter | somatic clone phenotype, enhanceable by N^VDRC.cUa, Scer\GAL4^NP5130

(Xu et al., 2018)

Scer\GAL4^NP5130, ct^HMS00924 has adult enteroendocrine cell | ectopic | somatic clone phenotype, enhanceable by N^VDRC.cUa, Scer\GAL4^NP5130

(Xu et al., 2018)

NOT Enhancer of

Statement

Reference

ct^HMS00924, Scer\GAL4^NP5130 is a non-enhancer of midgut | somatic clone phenotype of N^VDRC.cUa, Scer\GAL4^NP5130

(Xu et al., 2018)

Suppressor of

Statement

Reference

ct^HMS00924/Scer\GAL4^Mef2.PR is a suppressor of indirect flight muscle | adult stage phenotype of Scer\GAL4^Mef2.PR, salm^KK106735

(Katti et al., 2022)

ct^HMS00924/Scer\GAL4^Mef2.PR is a suppressor of mitochondrion | adult stage phenotype of Scer\GAL4^Mef2.PR, salm^KK106735

(Katti et al., 2022)

ct^HMS00924, Scer\GAL4^NP5130 is a suppressor of Malpighian tubule | somatic clone phenotype of N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^NP5130

(Xu et al., 2018)

NOT Suppressor of

Statement

Reference

ct^HMS00924, Scer\GAL4^NP5130 is a non-suppressor of midgut | somatic clone phenotype of N^VDRC.cUa, Scer\GAL4^NP5130

(Xu et al., 2018)

ct^HMS00924, Scer\GAL4^NP5130 is a non-suppressor of enteroendocrine cell | somatic clone phenotype of N^VDRC.cUa, Scer\GAL4^NP5130

(Xu et al., 2018)

Other

Statement

Reference

N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^NP5130, ct^HMS00924 has Malpighian tubule phenotype

(Xu et al., 2018)

N^{UAS.Tag:V5,Tag:polyHis}, Scer\GAL4^NP5130, ct^HMS00924 has enterocyte | ectopic phenotype

(Xu et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

The co-expression of ct^HMS00924 and N^{UAS.Tag:V5,Tag:polyHis} under the control of Scer\GAL4^esg-NP5130 leads to the abnormal differentiation of renal tubule progenitors into enterocyte-like cells (i.e. Pdm1-positive cells).

(Xu et al., 2018)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

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Mutant

Wild-type

Stocks (2)

Bloomington

33967