FlyBase Allele Report: Scer\GAL4[NP3056]

General Information

Symbol

Scer\GAL4^NP3056

Species

S. cerevisiae

Name

FlyBase ID

FBal0246718

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}CG2162^NP3056

Carried in Construct

Also Known As

NP3056-GAL4, NP3056

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GawB}CG2162^NP3056

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:3,038,396..3,038,396 [+]

(Aimino et al., 2023, Gugel et al., 2023, Parisi et al., 2023, Chen et al., 2019, Fulterer et al., 2018, Liou et al., 2018, Tsai et al., 2018, Nagel and Wilson, 2016, Mosca and Luo, 2014, Thum et al., 2011, Chou et al., 2010)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

embryonic/larval antennal lobe

(Thum et al., 2011)

neuron | subset of larval deutocerebrum

(Thum et al., 2011)

larval gnathal ganglion

(Thum et al., 2011)

adult stage

adult antennal lobe local neuron

(Chou et al., 2010)

GABAergic local interneuron of the adult antennal lobe | subset

Comment: 42 of 56 labeled neurons

(Chou et al., 2010)

cholinergic local interneuron of the adult antennal lobe | subset

Comment: 2 of 56 labeled neurons

(Chou et al., 2010)

glutamatergic local interneuron of the adult antennal lobe | subset

Comment: 3 of 58 labeled neurons

(Chou et al., 2010)

Additional Information

Statement

Reference

ScerGAL4^{CG2162-NP3056} drives expression in one to two neurons that innervate the larval antennal lobe (AL) and the subesophageal ganglion. The cell bodies labeled neurons are located lateral to the AL.

(Thum et al., 2011)

ScerGAL4^{CG2162-NP3056} drives expression in cell bodies found in the local interneuron cluster located lateral and dorsolateral to the antennal lobe, and is expressed in approximately 56 cells, most of which are ipsilaterally projecting.

(Chou et al., 2010)

ScerGAL4^{CG2162-NP3056} drives expression in mostly GABAergic antennal lobe local interneurons.

(Chou et al., 2010)

Marker for

Reflects expression of

CG2162

(Thum et al., 2011, Chou et al., 2010)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | adult stage, with Cbeta\DT^A-I.UAS

(Liou et al., 2018)

abnormal neuroanatomy | pupal stage, with EcR^{B1-ΔC655.F645A.UAS}

(Liou et al., 2018)

Phenotype Manifest In

adult antennal lobe, with Cbeta\DT^A-I.UAS

(Liou et al., 2018)

local interneuron of larval antennal lobe | pupal stage, with EcR^{B1-ΔC655.F645A.UAS}

(Liou et al., 2018)

Detailed Description

Statement

Reference

Ablation (using Cbβ\DT-A^I.UAS) of Scer\GAL4^NP3056 neurons, in combination with a Gal80[ts] transgene to restrict expression to between late third instar larva and 6.5 hours after puparium formation, results in differences in the relative distances between antennal lobe glomeruli, with general shifts along the dorsal-ventral and antero-posterior axes, compared to controls; there is no obvious mistargeting of projection neuron dendrites.

(Liou et al., 2018)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

113080

w^*; P{GawB}CG2162^NP3056

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^{CG2162-NP3056}

Scer\GAL4^NP3056

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

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