FB2024_03 , released June 25, 2024
Allele: Dmel\DgEx.UAS.Tag:FLAG
Open Close
General Information
Symbol
Dmel\DgEx.UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0246188
Feature type
allele
Associated gene
Dmel\Dg
Associated Insertion(s)
Carried in Construct
P{UAS-Dg.Ex}
Key Links
Transgenic product class
inframe_deletion
(Nakamura et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Nakamura et al., 2010)
Mutagen
in vitro construct
(Nakamura et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Dg.Ex}
Cytology
Description

UASt regulatory sequences drive expression of the first 1048 amino acid residues of the Dg-C isoform (the entire predicted extracellular domain) which is tagged with three copies of Tag:FLAG.

(Nakamura et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Dg
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of DgEx.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4Act5C.PI results in defective crossveins, with 12% of animals showing a loss of crossvein tissue in the wing.

      (Nakamura et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Phenotype Manifest In
      Enhanced by
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The penetrance of the loss of crossvein phenotype seen in the wings of animals expressing DgEx.Scer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4Act5C.PI is increased if they are simultaneously co-expressing both rtScer\UAS.cNa and twScer\UAS.T:Ivir\HA1.

      (Nakamura et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DgEx.Scer\UAS.T:Zzzz\FLAG
      DgEx.UAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)