FB2024_03 , released June 25, 2024
Allele: Dmel\Pdh+t1.5
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General Information
Symbol
Dmel\Pdh+t1.5
Species
D. melanogaster
Name
FlyBase ID
FBal0244066
Feature type
allele
Associated gene
Dmel\Pdh
Associated Insertion(s)
Carried in Construct
P{Pdh+t1.5}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Wang et al., 2010)
wild_type
(Wang et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Wang et al., 2010)
wild_type
(Wang et al., 2010)
Mutagen
in vitro construct
(Wang et al., 2010)
Progenitor genotype
Carried in construct
P{Pdh+t1.5}
Cytology
Description

A 1.5 kb DNA fragment carrying the -515 to +1035 region of Pdh (+1 is the transcription start site).

(Wang et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
Pdh
Encoded product / tool
Pdh
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3L:16,353,262..16,354,812 [-]
Comment:

The rescue fragment is reported to extend from -515 to +1035 relative to the Pdh transcription start site. The start of Pdh-RA was used as the transcription start site for the mapping.

(Wang et al., 2010)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Pdh+t1.5 rescues Pdh1

      (Wang et al., 2010)
      Comments

      The observed loss of deactivation afterpotential in electroretinogram recordings in older Pdh1 mutant flies is rescued by Pdh+t1.5.

      (Wang et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Pdh+t1.5
      Name Synonyms
      Secondary FlyBase IDs
        References (1)