FB2024_03 , released June 25, 2024
Allele: Dmel\SuUR1-599.UAS
Open Close
General Information
Symbol
Dmel\SuUR1-599.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0242591
Feature type
allele
Associated gene
Dmel\SuUR
Associated Insertion(s)
Carried in Construct
P{UAS-SuUR.1-599}
Key Links
Transgenic product class
stop_gained
(Kolesnikova et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
stop_gained
(Kolesnikova et al., 2005)
Mutagen
ethyl methanesulfonate
(Kolesnikova et al., 2005)
Progenitor genotype
SuURUAS.cZa
(Kolesnikova et al., 2005)
Carried in construct
P{UAS-SuUR.1-599}
Cytology
Description

A premature stop codon has been introduced into the SuUR sequences (at codon 600), resulting in the expression of a truncated protein from the construct.

(Kolesnikova et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
SuUR
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of SuUR1-599.Scer\UAS under the control of Scer\GAL4AB1 results in the disappearance of weak points in the polytene chromosomes of salivary glands.

      Expression of SuUR1-599.Scer\UAS under the control of Scer\GAL4Sgs3.PD in a SuURES background results in large swellings in the chromocenter and intercalary heterochromatin regions of polytene chromosomes in the salivary glands. The chromosomes spread poorly in squashes, because of numerous ectopic contacts.

      (Kolesnikova et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SuUR1-599.Scer\UAS
      SuUR1-599.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)