A premature stop codon has been introduced into the SuUR sequences (at codon 459), resulting in the expression of a truncated protein from the construct.
Expression of SuUR1-458.Scer\UAS under the control of Scer\GAL4AB1 results in the disappearance of weak points in the polytene chromosomes of salivary glands.
Expression of SuUR1-458.Scer\UAS under the control of Scer\GAL4AB1 results in the disappearance of weak spots on both homologs in polytene chromosomes of D.melanogaster x D.simulans hybrids.