FB2024_03 , released June 25, 2024
Allele: Dmel\CkaHM05138
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General Information
Symbol
Dmel\CkaHM05138
Species
D. melanogaster
Name
FlyBase ID
FBal0240267
Feature type
allele
Associated gene
Dmel\Cka
Associated Insertion(s)
Carried in Construct
P{TRiP.HM05138}
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.HM05138}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-HM05138
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of CkaHM05138 under the control of Scer\GAL4Mef2.PR leads to indirect flight muscle atrophy during pupal development (after 32h APF); fibers are longer than in controls and fail to compact at 32h APF.

      (Kaya-Çopur et al., 2021)

      Expression of CkaHM05138 under the control of Scer\GAL4RapGAP1-OK6 results in a significant increase in the number of satellite boutons on neuromuscular junctions in third instar larval muscles.

      (Sakuma et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      CkaHM05138, Scer\GAL4Mef2.PR has increased body size | P-stage phenotype, enhanceable by NuakK99R

      (Guo et al., 2023)
      NOT Enhanced by
      Statement
      Reference

      CkaHM05138, Scer\GAL4Mef2.PR has increased body size | P-stage phenotype, non-enhanceable by stv1

      (Guo et al., 2023)
      NOT suppressed by
      Statement
      Reference

      CkaHM05138, Scer\GAL4Mef2.PR has increased body size | P-stage phenotype, non-suppressible by stv1

      (Guo et al., 2023)
      NOT Enhancer of
      Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The increased number of satellite boutons on neuromuscular junctions in third instar larvae expressing StripdsRNA.shRNA.Scer\UAS.9 under the control of Scer\GAL4RapGAP1-OK6 is not further enhanced by co-expression of CkaHM05138.

      (Sakuma et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      CkaHM05138
      (Neisch et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (10)