FB2024_03 , released June 25, 2024
Allele: Dmel\PtthKK110502
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General Information
Symbol
Dmel\PtthKK110502
Species
D. melanogaster
Name
FlyBase ID
FBal0236889
Feature type
allele
Associated gene
Dmel\Ptth
Associated Insertion(s)
Carried in Construct
P{KK110502}
Also Known As
UAS-Ptth-RNAi, ptth-RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Keleman et al., 2009.8.5)
Mutagen
in vitro construct
(Keleman et al., 2009.8.5)
Progenitor genotype
Carried in construct
P{KK110502}
Cytology
Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dsRNA-KK110502
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of PtthKK110502 under the control of Scer\GAL4NP0394 (which is variegated) results in smaller prothoracic gland lobe, cells and nuclei, as compared with neighboring non-expressing lobe or cells.

      (Shimell et al., 2018)

      Expression of PtthKK110502 under the control of Scer\GAL4Ptth.cMa significantly reduces the circadian rhythmicity of adult emergence after transfer to constant darkness, compared to controls.

      (Selcho et al., 2017)

      Expression of PtthKK110502 under the control of Scer\GAL4nSyb.PU (in combination with UAS-Dicer2 to increase RNAi efficiency) does not result in a significant change in the latency to sperm ejection in females after the end of copulation.

      (Lee et al., 2015)

      Expression of Scer\GAL4NP0423>PtthKK110502 results in impaired light avoidance in feeding larvae.

      Expression of Scer\GAL4αTub84B.PL>PtthKK110502 results in impaired light avoidance in feeding larvae.

      (Yamanaka et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      When exposed to a light/dark choice, wild-type larvae show a strong preference to pupariate in the dark. This behaviour is abolished by the expression of PtthKK110502 and Dcr-2Scer\UAS.cDa under the control of Scer\GAL4NP0423.

      (Yamanaka et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      PtthKK110502
      Name Synonyms
      Secondary FlyBase IDs
        References (8)