UASt regulatory sequences drive expression of an inverted repeat.
Expression of mysKK100518 driven by Scer\GAL4Hand.PU causes complete retraction of myofibrils and actin accumulation around the nucleus of the cardiomyocyte.
Expressing mysKK100518 under the control of Scer\GAL4repo (in combination with a Dicer-2 transgene to enhance RNAi efficiency) results in decreased glial cell numbers and an abnormal distribution of glial cells in the eye discs of second and third instar larvae. Together with a lack of cell death, this points towards defective cell migration. Photoreceptor axon attachment to the neural lamella and targeting to the optic stalk are unaffected.
Third instar larvae expressing mysKK100518 under the control of Scer\GAL4repo exhibit unwrapped, defasciculated and disorganized photoreceptor axon bundles, and a severely reduced fenestrated membrane in eye discs. The neural lamella is unaffected.
Expression of mysKK100518 under the control of Scer\GAL4Bx-MS1096 causes 'burned' (warped and dusky) wings throughout adult life.
Embryos expressing mysKK100518 under the control of Scer\GAL4Mef2.PR show small clumps or gaps in the rows of cardioblasts in the heart region of the dorsal vessel.
Scer\GAL4GMR.long/mysKK100518 is an enhancer of eye phenotype of Scer\GAL4GMR.long, parvinUASp.mGFP6