dndd10234 is caused by P-element P{XP}CG6678d10234 inserted between the genes dnd and CG6678 leaving their protein coding regions intact.
P{XP}CG6678d10234 is located 163bp upstream of dnd and affects dnd expression.
Homozygous dndd10234 embryos undergo apparently normal fusion of tracheal branches in the dorsal trunk.
dndd10234 mutant embryos display tracheal dorsal branch and dorsal trunk fusion defects. Dorsal branch lumenal breaks are observed in 80% of segments, and dorsal trunk constrictions are observed in 70% of segments at fusion sites.
dndd10234 is partially rescued by dndUAS.cJa/Scer\GAL4esg-p127
dndd10234 is partially rescued by Scer\GAL4esg-p127/dndG2A.UAS
dndd10234 is partially rescued by dndT31N.UAS.cJa/Scer\GAL4esg-p127
dndd10234 is partially rescued by Scer\GAL4esg-p127/dndQ71L.UAS.cJa
Scer\GAL4p127 driven expression of dndScer\UAS.cJa partially rescues the tracheal dorsal branch fusion defects found in dndd10234 mutant embryos from 80% to 13%.
Scer\GAL4p127 driven expression of dndG2A.Scer\UAS rescues the tracheal dorsal branch fusion defects found in dndd10234 mutant embryos from 20% to 79% fused.
Scer\GAL4p127 driven expression of dndT31N.Scer\UAS.cJa rescues the tracheal dorsal branch fusion defects found in dndd10234 mutant embryos from 20% to 41% fused.
Homozygous dndd10234 embryos express a detectable amount of dnd in their tracheal fusion cells.