Insertion in an intron between coding exons for the "Sls" and "Kettin" isoforms of sls.
slsZCL2144, Df(3R)Exel6176 double heterozygotes model myopathy.
slsZCL2144 heterozygotes do not exhibit obvious defects in adult indirect flight muscles, as compared to controls.
Df(3R)Exel6176/+, slsZCL2144 has sarcomere | adult stage phenotype, enhanceable by cher[+]/cherQ1042X
Df(3R)Exel6176/+, slsZCL2144 has H zone | adult stage phenotype, enhanceable by cher[+]/cherQ1042X
Df(3R)Exel6176/+, slsZCL2144 has indirect flight muscle cell | adult stage phenotype, enhanceable by cher[+]/cherQ1042X
Df(3R)Exel6176/+, slsZCL2144 has sarcomere | adult stage phenotype, enhanceable by cherEPSΔ5/cher[+]
Df(3R)Exel6176/+, slsZCL2144 has H zone | adult stage phenotype, enhanceable by cherEPSΔ5/cher[+]
Df(3R)Exel6176/+, slsZCL2144 has indirect flight muscle cell | adult stage phenotype, enhanceable by cherEPSΔ5/cher[+]
Df(3R)Exel6176/+, slsZCL2144 has sarcomere | adult stage phenotype, enhanceable by cher[+]/chersko
Df(3R)Exel6176/+, slsZCL2144 has H zone | adult stage phenotype, enhanceable by cher[+]/chersko
Df(3R)Exel6176/+, slsZCL2144 has indirect flight muscle cell | adult stage phenotype, enhanceable by cher[+]/chersko
Df(3R)Exel6176/+, slsZCL2144 has sarcomere | adult stage phenotype
Df(3R)Exel6176/+, slsZCL2144 has indirect flight muscle cell | adult stage phenotype
Df(3R)Exel6176/+, slsZCL2144 has H zone | adult stage phenotype
slsZCL2144, Df(3R)Exel6176 double heterozygotes frequently exhibit a lack of separation of individuals sarcomeres and accumulation of actin in the H-zone of adult indirect flight muscles, as compared to controls; this actin defect is enhanced by the additional presence of one copy of cherQ1042X, cherEPSΔ5, or chersko. slsZCL2144, cherCPTI001403 double heterozygotes, however, do not exhibit any obvious sarcomere defects, as compared to controls.