FB2024_03 , released June 25, 2024
Allele: Scer\GAL4NP0509
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General Information
Symbol
Scer\GAL4NP0509
Species
S. cerevisiae
Name
FlyBase ID
FBal0221513
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
P{GawB}Mmp2NP0509
Carried in Construct
Also Known As
mmp2-Gal4, E0564-Gal4
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GawB}Mmp2NP0509
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Inserted element
    P{GawB}
    Encoded product / tool
    GAL4
    Mutations Mapped to the Genome
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        distribution deduced from reporter (Gal4 UAS)
        Stage
        Tissue/Position (including subcellular localization)
        Reference
        third instar larval stage
        peripodial stalk of wing disc
        (Srivastava et al., 2007)
        air sac primordium | distal
        (Wang et al., 2010)
        air sac primordium tip cell
        (Wang et al., 2010)
        CNS surface glial cell
        (Olson et al., 2019)
        photoreceptor precursor cell
        (Olson et al., 2019)
        adult stage
        neuron | subset of adult brain
        (Lai et al., 2012)
        antennal mechanosensory and motor center B1a projection neuron
        (Lai et al., 2012)
        adult multiglomerular antennal lobe projection neuron
        (Lin et al., 2013)
        adult lateral antennal lobe tract
        (Lin et al., 2013)
        superior medial protocerebrum
        (Lin et al., 2013)
        superior clamp
        (Lin et al., 2013)
        posterior superior lateral protocerebrum
        (Lin et al., 2013)
        adult lateral horn
        (Lin et al., 2013)
        adult multiglomerular antennal lobe projection neuron | subset
        (Tanaka et al., 2012)
        antennal lobe hub | restricted
        (Tanaka et al., 2012)
        day 1 of adulthood
        epithelium
        (Yasunaga et al., 2010)
        Additional Information
        Statement
        Reference

        ScerGAL4Mmp2-NP0509 drives expression in around 9 laterally positioned adult multiglomerular antennal lobe projection neurons innervating all antennal lobe glomeruli and the antennal lobe hub.

        (Tanaka et al., 2012)

        Mmp2 reporter is expressed in the air sac primordium in third instar larvae and becomes progressively more prominent at the distal end of the air sac and in the tip cells.

        (Wang et al., 2010)

        Only weak expression of Mmp2 reporter is observed at late pupal stages. Expression is significantly elevated at the early adult stage (0-4 hr after eclosion) and returns to the basal level three days after eclosion. Mmp2 appears to be transiently upregulated in epithelial cells during 24 hours after eclosion.

        (Yasunaga et al., 2010)
         
        Marker for
        antennal mechanosensory and motor center B1a projection neuron
        (Lai et al., 2012)
        Reflects expression of
        Mmp2
        (Lin et al., 2013, Wang et al., 2010, Yasunaga et al., 2010, Srivastava et al., 2007)
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Blockade of PNv2 (by expressing the temperature sensitive shits.UAS.cUa under the control of Scer\GAL4NP0509 and shifted to the permissive 33[o]C) abolishes odor acuity.

        (Muria et al., 2021)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Scer\GAL4Mmp2-NP0509
        Scer\GAL4NP0509
        Name Synonyms
        Secondary FlyBase IDs
          References (15)