Expression of poloScer\UAS.P\T.cXa under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 results in a dosage-dependent increase in the frequency of achiasmate X and 4th chromosome nondisjunction in In(1)FM7/X females compared to controls (the In(1)FM7 chromosome is present to fully suppress X chromosomal exchange).
Scer\GAL4VP16.nanos.UTR/poloUASp.cXa is an enhancer of oocyte nucleus | oogenesis stage S12 phenotype of mtrm126
Scer\GAL4VP16.nanos.UTR, mtrm126, poloUASp.cXa has oocyte nucleus | oogenesis stage S11 phenotype
Expression of poloScer\UAS.P\T.cXa under the control of Scer\GAL4tin.D partially rescues the severity of the cardiac defects seen in Df(3R)Exel6157 and in Df(1)CHES-1-like1 embryos. Both the defects in asymmetric cell division and in symmetric cell division seen in the cardiac progenitors are rescued.
The precocious nuclear envelope breakdown (NEB) seen in oocytes of mtrm126/+ females is enhanced by expression of poloScer\UAS.P\T.cXa under the control of Scer\GAL4nos.UTR.T:Hsim\VP16; the frequency of NEB in stage 12 oocytes is increased to 77%, and NEB is seen in 19% of stage 11 oocytes.