FB2024_03 , released June 25, 2024
Allele: Dmel\GSd481GSd481
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General Information
Symbol
Dmel\GSd481GSd481
Species
D. melanogaster
Name
FlyBase ID
FBal0218724
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Isolated RP2 neuron clones expressing GSd481GSd481 under the control of Scer\GAL4Act5C.PP (clones generated using the Scer\FLP1eve.RN2 line) show a reduction in dendrite growth at 25-31 hours after egg laying. The distribution of dendrites in the dendritic field is altered: there is a decrease in the number of dendrites targeted to the anterior, posterior, medial and lateral regions of the dendritic field.

    Fas2-positive axon bundles in the ventral nerve cord are diffuse or less distinct than normal in embryos expressing GSd481GSd481 under the control of Scer\GAL4scrt-11-6.

    External Data
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    Show genetic interaction network for Enhancers & Suppressors
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    Xenogenetic Interactions
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    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer

    The "GSd481" line contains two insertions (P{GSV1}GSd481a and P{GSV1}GSd481b) and it is not known which insertion is responsible for the lethality and other phenotypes seen in combination with the Scer\GAL4scrt-11-6 driver. FlyBase curator comment: a GSd481GSd481 allele has been made to accommodate the overexpression phenotypes, until it is known which (or both) insertions cause them.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    GSd481GSd481
    Name Synonyms
    Secondary FlyBase IDs
      References (3)