FB2024_03 , released June 25, 2024
Allele: Dmel\dxUAS.Tag:FLAG
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General Information
Symbol
Dmel\dxUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0217805
Feature type
allele
Associated gene
Dmel\dx
Associated Insertion(s)
Carried in Construct
P{UAS-dx.FLAG}
Also Known As
UAS-FLAG-Dx
Key Links
Transgenic product class
cDNA
(Mukherjee et al., 2005)
wild_type
(Mukherjee et al., 2005)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Mukherjee et al., 2005)
wild_type
(Mukherjee et al., 2005)
Mutagen
in vitro construct
(Mukherjee et al., 2005)
Progenitor genotype
Carried in construct
P{UAS-dx.FLAG}
Cytology
Description

Expression of dx cDNA, fused in frame at the N-terminus to the Tag:FLAG epitope is under the control of UASt sequences.

(Mukherjee et al., 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dx
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of dxScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4bbg-C96 results in mild irregularities in bristle patterning along the wing margin.

      Expression of dxScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4A9 results in loss of vein material at the distal end of the L4 and L5 wing veins, with moderate loss in bristle pattern along the wing margin.

      (Mishra et al., 2014)

      krzScer\UAS.T:Ivir\HA1; Scer\GAL4C-96 flies mild irregularities in patterning of the anterior wing margin.

      (Mukherjee et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhanced by
      Suppressed by
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Traf6Scer\UAS.T:Ivir\HA1.cMa does not alter the wing nicking phenotype seen when krzScer\UAS.T:Ivir\HA1 and dxScer\UAS.T:Zzzz\FLAG are expressed under the control of Scer\GAL4bbg-C96.

      One copy of Traf6ex1 partially suppresses the wing nicking phenotype seen when krzScer\UAS.T:Ivir\HA1 and dxScer\UAS.T:Zzzz\FLAG are expressed under the control of Scer\GAL4bbg-C96. The resulting flies exhibit loss of L4 vein material.

      Expression of Traf6dsRNA.Scer\UAS partially suppresses the wing nicking phenotype seen when krzScer\UAS.T:Ivir\HA1 and dxScer\UAS.T:Zzzz\FLAG are expressed under the control of Scer\GAL4bbg-C96. The resulting flies exhibit loss of L4 vein material.

      Co-expression of Traf6Scer\UAS.T:Ivir\HA1.cMa and dxScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4bbg-C96 results in notching around the entire wing margin.

      Co-expression of Traf6Scer\UAS.T:Ivir\HA1.cMa and dxScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4A9 results in a severely deformed wing.

      Co-expression of Traf6Scer\UAS.T:Ivir\HA1.cMa and dxScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4en.PU results in a shift in the anterior-posterior boundary of the wing disc towards the posterior side.

      (Mishra et al., 2014)

      krzScer\UAS.T:Ivir\HA1; dxScer\UAS.T:Zzzz\FLAG/Scer\GAL4C-96 flies have severely notched wings.

      (Mukherjee et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      dxScer\UAS.T:Zzzz\FLAG
      dxUAS.T:Zzzz\FLAG
      dxUAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (4)