FB2024_03 , released June 25, 2024
Allele: Dmel\mre11unspecified
Open Close
General Information
Symbol
Dmel\mre11unspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0217452
Feature type
allele
Associated gene
Dmel\mre11
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In

        chromosome & neuroblast | third instar larval stage 2

        (Bi et al., 2005)
        Detailed Description
        Statement
        Reference

        The chromosomes of third instar larval neuroblasts of mre11unspecified mutants frequently have fused ends.

        (Bi et al., 2005)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Enhanced by
        Statement
        Reference

        mre11unspecified has chromosome & neuroblast | third instar larval stage 2 phenotype, enhanceable by mus304D1/mus304D1

        (Bi et al., 2005)
        NOT Enhanced by
        Statement
        Reference

        mre11unspecified has chromosome & neuroblast | third instar larval stage 2 phenotype, non-enhanceable by lokp6

        (Bi et al., 2005)

        mre11unspecified has chromosome & neuroblast | third instar larval stage 2 phenotype, non-enhanceable by grp06034

        (Bi et al., 2005)
        NOT Enhancer of
        Statement
        Reference

        mre11unspecified is a non-enhancer of chromosome & neuroblast | third instar larval stage 2 phenotype of nbs1

        (Bi et al., 2005)
        NOT Suppressor of
        Statement
        Reference

        mre11unspecified is a non-suppressor of chromosome & neuroblast | third instar larval stage 2 phenotype of nbs1

        (Bi et al., 2005)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        mre11unspecified does not override the reduced mitotic index of seaEP3364 single mutants.

        (Morciano et al., 2009)

        The chromosome fusion phenotype seen in the nuclei of third instar larval neuroblasts of mre11unspecified mutants is enhanced by mus304D1/mus304D1 but not by grp06034 or lokp6.

        mre11unspecified does not enhance or suppress the telomere fusion phenotype seen in third instar larval neuroblasts due to nbs1.

        (Bi et al., 2005)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        mre11unspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (2)