FB2024_03 , released June 25, 2024
Allele: Dmel\MhcIfm(2)RU1-3
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General Information
Symbol
Dmel\MhcIfm(2)RU1-3
Species
D. melanogaster
Name
FlyBase ID
FBal0217345
Feature type
allele
Associated gene
Dmel\Mhc
Associated Insertion(s)
Carried in Construct
Also Known As
ifm(2)RU13
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Babu and Ramachandra, 2004)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The dorsal longitudinal muscles of the indirect flight muscles are not completely denatured, but anterior regions in the thoracic musculature show degeneration. The flies are rendered flightless. Dorsoventral muscles are wildtype.

      (Babu and Ramachandra, 2007)

      Mutants have defective dorsal longitudinal muscles (DLMs) with considerable thinning of the fibres. The fibres are disrupted, appear to be loosely bundled and show degeneration in the posterior region of the thorax. All six fibres of the DLMs are formed. The dorsoventral muscles show slight thinning but are otherwise normal.

      (Babu and Ramachandra, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ifm(2)RU13
      MhcIfm(2)RU1-3
      ifm(2)RU13
      (Babu and Ramachandra, 2007, Babu and Ramachandra, 2004)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)