FB2024_03 , released June 25, 2024
Allele: Dmel\bocksDP01391
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General Information
Symbol
Dmel\bocksDP01391
Species
D. melanogaster
Name
FlyBase ID
FBal0216556
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    Cytology
    Description
    Allele components
    Component
    Use(s)
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
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    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    bocksDP01391 homozygotes exhibit nuclear positioning defects in muscles. Larval VL3 muscles present significantly shorter internuclear distances, longer nucleus-muscle edge distance, and significantly shorter distance between nuclear lines, as compared to controls; heterozygotes also show a significantly shorter internuclear distance, as compared to controls. Homozygous embryonic LT muscles exhibit nucleus clustering near the ventral end of the muscle (the initial nucleus cluster fails to separate into ventral and dorsal clusters) or unequally distributed along the muscle, but no changes in nucleus:muscle area ratio, as compared to controls.

    External Data
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    Xenogenetic Interactions
    Statement
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    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    bocksDP01391
    bocksbeutelDP01391
    Name Synonyms
    Secondary FlyBase IDs
      References (2)