FlyBase Allele Report: Dmel\Apc2[5-3]

General Information

Symbol

Dmel\Apc2^5-3

Species

D. melanogaster

Name

FlyBase ID

FBal0213109

Feature type

allele

Associated gene

Dmel\Apc2

Associated Insertion(s)

P{?EP}Apc2^5-3

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - genetic evidence

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Takacs et al., 2008)

Mutagen

Delta2-3 transposase

(Takacs et al., 2008)

Progenitor genotype

P{EP}Apc2^G5028

(Takacs et al., 2008)

Associated Insertion(s)

P{?EP}Apc2^5-3

Cytology

Description

Imprecise excision of the P{EP}Apc2^G5028 insertion such that 5159 nucleotides of the original insertion remain.

(Takacs et al., 2008)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

delins

3R:24,164,024..24,164,024 [+]

Comment:

5159 nucleotides remain at the site of the imprecise excision of P{EP}Apc2^G5028.

(Takacs et al., 2008)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Apc2³³/Apc2^5-3, Apc^Q8 has visible phenotype

(Takacs et al., 2008)

Apc2^5-3, Apc^Q8 has visible phenotype

(Takacs et al., 2008)

Apc2^G5028/Apc2^5-3, Apc^Q8 has visible phenotype

(Takacs et al., 2008)

Apc2^19-3/Apc2^5-3, Apc^Q8 has visible phenotype

(Takacs et al., 2008)

Phenotype Manifest In

Other

Statement

Reference

Apc2³³/Apc2^5-3, Apc^Q8 has sternite phenotype

(Takacs et al., 2008)

Apc2³³/Apc2^5-3, Apc^Q8 has abdominal sternite bristle | ectopic phenotype

(Takacs et al., 2008)

Apc2³³/Apc2^5-3, Apc^Q8 has pleural membrane phenotype

(Takacs et al., 2008)

Apc2^5-3, Apc^Q8 has abdominal sternite bristle phenotype

(Takacs et al., 2008)

Apc2^5-3, Apc^Q8 has sternite phenotype

(Takacs et al., 2008)

Apc2^5-3, Apc^Q8 has pleural membrane phenotype

(Takacs et al., 2008)

Apc2^G5028/Apc2^5-3, Apc^Q8 has abdominal sternite bristle phenotype

(Takacs et al., 2008)

Apc2^G5028/Apc2^5-3, Apc^Q8 has sternite phenotype

(Takacs et al., 2008)

Apc2^G5028/Apc2^5-3, Apc^Q8 has pleural membrane phenotype

(Takacs et al., 2008)

Apc2^19-3/Apc2^5-3, Apc^Q8 has wing phenotype

(Takacs et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Apc^Q8 Apc2^5-3/Apc^Q8 Apc2³³ double mutants show expansion of sternal territory in the abdomen and ectopic sternal bristles, at the expense of the pleura.

(Takacs et al., 2008)

Apc^Q8 Apc2^5-3 double homozygotes show loss of sternites and sternal bristles and expansion of the pleura in the abdomen.

Apc^Q8 Apc2^5-3/Apc^Q8 Apc2^G5028 double mutants show loss of sternites and sternal bristles and expansion of the pleura in the abdomen.

Apc^Q8 Apc2^5-3/Apc^Q8 Apc2^19-3 double mutants show a wing to notum transformation.

(Takacs et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Apc2^5-3

(Takacs et al., 2008, Takacs et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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