Amino acid replacement: S178F.
Nucleotide substitution: ??T.
C20790473T
??T
S345F | vari-PB; S178F | vari-PC; S324F | vari-PD; S345F | vari-PE; S178F | vari-PF
S178F
Mutants show defects in septate junction barrier function (as tested using a dye exclusion assay).
Mutants have strong tracheal defects.