UASt regulatory sequences drive expression of an inverted repeat.
Imaginal disc cells expressing stgGD8177, under the control of Scer\GAL4en.PU or Scer\GAL4hh.PU experience a shorter G[[2]] phase and exhibit some DNA damage and cell death.
Expression under the control of Scer\GAL4pnr-MD237 results in loss of bristles on the notum in 70-80% of the Scer\GAL4pnr-MD237 expression domain.
Expression under the control of Scer\GAL4pnr-MD237 results in bristle morphology defects on the notum in 30-40% of the Scer\GAL4pnr-MD237 expression domain.
The cell death and DNA damage seen in imaginal disc cells expressing stgGD8177, under the control of Scer\GAL4en.PU or Scer\GAL4hh.PU is strongly enhanced by expression of mad2GD16427, which induced chromosomal instability.