UASt regulatory sequences drive expression of an inverted repeat.
Adults expressing l(2)k01209GD11430 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) can show significantly reduced avoidance of noxious temperature (46[o]C) compared to control flies, depending on the particular P{GD11430} insertion line used.
Adults expressing l(2)k01209GD11430 under the control of Scer\GAL4elav.PLu (in the presence of Dcr-2Scer\UAS.cDa to increase the efficiency of RNAi) show no significant change in the kinetics of high temperature (46[o]C) induced paralysis compared to control flies.
Expression under the control of Scer\GAL4Mef2.PR results in early pupal lethality.